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A numbing medicine turned a woman's blood blue

Bluehost does not offer any refunds for cancellations that occur after 30 days. The diagnosis prompted Warren to take a more precise measurement of the woman's blood oxygen level, which showed that it was in fact much lower, at 67 percent.

At this level, tissue damage can occur. Instead, she had used an over-the-counter numbing medication, which contained benzocaine, to help with pain from a toothache.

Methemoglobinemia is easily treatable, using a medication that, perhaps ironically, is called methylene blue. The woman was given the drug intravenously, and within minutes reported feeling better. Still, she was given a second dose and spent the night in the hospital for observation before being sent home the next morning with a referral to a dentist. The case spurred Warren to keep an eye for products containing benzocaine.


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The strange reaction is also unpredictable. Benzocaine is not the only drug that can cause methemoglobinemia. It can occur at low or high doses, and can happen even if a person has used the drugs previously with no reaction. While these reactions are rare, the Food and Drug Administration has issued past warnings to hospitals, noting that benzocaine can lead to methemoglobinemia. The FDA also recommends that teething products containing benzocaine should not be given to children under 2.

Warren said that, in his hospital, he's noticed the spray cans containing benzocaine have gotten much smaller. This may be to reduce the risk of giving too much, he said. Methemoglobinemia isn't only caused by numbing agents.

The condition can also be caused by certain antibiotics or contaminated well water.